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Safranin

CAT: 0804-HY-D0215-01Size: 50 gDry Ice: NoHazardous: No
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CAT#:0804-HY-D0215-01Size:50 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Safranin (Safranin T) is an important and classical phenazinium dye. Safranin has been extensively used in the academic field as a spectroscopic probe and indicator. Safranin possesses a planar structure and cationic charge. Safranin can readily intercalate into biological macromolecules, including DNA and proteins. Safranin has antibacterial effects against gram-positive bacteria (S. aureus) . Safranin can be used as a redox indicator in the determination of metal ion concentration[1][2][3][4].
CAS Number
477-73-6
Product Name Alternative
Safranine T
UNSPSC
12171500
Hazard Statement
H318
Target
Bacterial; Fluorescent Dye
Type
Dye Reagents
Related Pathways
Anti-infection; Others
Field of Research
Infection; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/safranin.html
Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CC1=CC2=NC3=C([N+](C4=CC=CC=C4)=C2C=C1N)C=C(N)C(C)=C3.[Cl-]
Molecular Formula
C20H19ClN4
Molecular Weight
350.85
Precautions
H318
References & Citations
[1]Wan H, et al. Structure characterization and optical properties investigation of the four main components of the classical phenazinium dye Safranin O. Analyst. 2019;144 (24) :7149-7156. |[2]Swain D, et al. Differential staining of the cell cycle of plant cells using safranin and indigo-picrocarmine. Stain Technol. 1990;65 (4) :197-204.|[3]Krumschnabel G, et al. Use of safranin for the assessment of mitochondrial membrane potential by high-resolution respirometry and fluorometry. Methods Enzymol. 2014;542:163-81.|[4]Al-Khikani F, et al. The Antibacterial Action of Safranin and Gentian Violet. Rambam Maimonides Med J. 2022 Jul 31;13 (3) :e0018.
Shipping Conditions
Room Temperature
Storage Conditions
RT, sealed storage, away from moisture and light
Scientific Category
Dye Reagents
Clinical Information
No Development Reported

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