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E1R

CAT: 0804-HY-116463-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-116463-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
E1R is a positive allosteric modulator of sigma-1 receptors (Sig1R PAM) with cognition-enhancing activity[1].
CAS Number
1301211-78-8
Product Name Alternative
MK-0869; MK-869; L-754030
UNSPSC
12352005
Target
Sigma Receptor
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/e1r.html
Concentration
10mM
Purity
99.83
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(CN1C(C[C@@H]([C@@H]1C)C2=CC=CC=C2)=O)N
Molecular Formula
C13H16N2O2
Molecular Weight
232.28
References & Citations
[1]Zvejniece L, et al. The cognition-enhancing activity of E1R, a novel positive allosteric modulator of sigma-1 receptors. Br J Pharmacol. 2014 Feb;171 (3) :761-71.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Sigma 1 Receptor

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