FITC-Dextran (MW 4000)

FITC-Dextran (MW 4000)

• CAS Number: 60842-46-8
• UNSPSC Description: FITC-Dextran (MW 4000) is a fluorescent probe for fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm). FITC-Dextran (MW 4000) can be used as a marker to reveal heat shock-induced cell damage and to study the early and late stages of apoptosis. FITC-Dextran (MW 4000) can also be used for cell permeability studies, such as blood-brain barrier permeability and determination of the extent of blood-brain barrier disruption[1][2][3].
• Target Antigen: Fluorescent Dye
• Type: Dye Reagents
• Related Pathways: Others
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/fitc-dextran-mw-4000.html
• Solubility: DMSO : 12.5 mg/mL (ultrasonic;warming;heat to 60°C)|H2O : 16.67 mg/mL (ultrasonic)
• Smiles: [FITC-Dextran (MW 4000)]
• Molecular Weight: 4000.00(Average)
• References & Citations: [1]Natarajan R, et al. Fluorescein Isothiocyanate (FITC)-Dextran Extravasation as a Measure of Blood-Brain Barrier Permeability. Curr Protoc Neurosci. 2017 Apr 10;79:9.58.1-9.58.15.|[2]Eriksson I, et al. Analysis of Lysosomal pH by Flow Cytometry Using FITC-Dextran Loaded Cells. Methods Mol Biol. 2017;1594:179-189.|[3]Moumaris M, et al. Fluorescein isothiocyanate-dextran can track apoptosis and necrosis induced by heat shock of peripheral blood mononuclear cells and HeLa cells[J]. Open Biological Sciences Journal, 2015, 1(1).|[4]Okabayashi K, et al. Cdc42 activates paracellular transport in polarised submandibular gland cells. Arch Oral Biol. 2021 Dec;132:105276.|[5]Yu W, et al. ACE2 contributes to the maintenance of mouse epithelial barrier function. Biochem Biophys Res Commun. 2020 Dec 17;533(4):1276-1282.Biochem Biophys Res Commun. 2020 Dec 17;533(4):1276-1282.|Biochem Biophys Res Commun. 2024 Sep 3:723:150176.|Bioengineered. 2022 Feb;13(2):3680-3693.|Bioengineered. 2022 Mar;13(3):7209-7220.|Biomaterials. 1 June 2022, 121608.|Biomed Pharmacother. 2024 Apr 25:175:116633.|Brain Behav Immun. 2023 Feb 27;S0889-1591(23)00050-8.|Cell Rep. 2023 Apr 4;42(4):112346.|Cell Rep. 2023 Jun 20;42(7):112660.|Curr Issues Mol Biol. 2022 Nov 29;44(12):5995-6005.|Device. 2024 June 12|EBioMedicine. 2022 Jul 28;82:104181.|Exp Brain Res. 2021 Jan;239(1):341-350.|FEBS J. 2024 Sep 15.|Food Funct. 23rd October 2021.|Front Pharmacol. 02 November 2021.|Gut Microbes. 2024 Jan-Dec;16(1):2377576.|Int Immunopharmacol. 2024 May 23:135:112263.|J Ethnopharmacol. 2023 Aug 26;117098.|J Ethnopharmacol. 2023 Dec 18:117567.|J Ethnopharmacol. 2024 Oct 16;337(Pt 3):118937.|Mol Med Rep. 2024 Jun;29(6):90.|Mol Neurobiol. 2024 Oct 17.|Mucosal Immunol. 2024 Sep 6:S1933-0219(24)00093-X.|Neurotox Res. 2022 May 7.|Pharmacol Res. 2024 May 21:205:107229.|Phytomedicine. 2023 Apr 21, 154825.|Res Sq. 2024 Aug 13.|Research Square Preprint. 2023 Oct 10.|Research Square Preprint. 2023 Oct 23.|Research Square Preprint. 2024 Apr 9.|Sci Adv. 2023 Oct 20;9(42):eadi0699.|Adv Sci (Weinh). 2021 Aug 16;e2101912.|Cancer Lett. 2024 Apr 16:591:216897.|Cell Tissue Res. 2022 Jul 4.|Ecotoxicol Environ Saf. 2024 Aug 16:284:116874.|Ecotoxicol Environ Saf. 2024 Jul 23:282:116762.|Exp Brain Res. 2021 Jan;239(1):341-350.|Front Pharmacol. 2024 Aug 29:15:1428572.|Heliyon. 2023 Jul 13.|Immun Inflamm Dis. 07 September 2022.|Immun Inflamm Dis. 2024 Dec;12(12):e70107.|Immunobiology. 2022: 152315.|J Funct Foods. 2024 Nov.|J Steroid Biochem Mol Biol. 2023 Apr 21;106314.|J Tradit Complement Med. 2024 Apr 29.|J Transl Med. 2024 Jun 5;22(1):535.|Kaohsiung J Med Sci. 2024 Jun 5.|Nat Commun. 2024 Jan 19;15(1):613.|Nat Metab. 2022 Sep;4(9):1138-1149.|Research Square Print. 2023 Feb 23.|SSRN. 2023 Jun 12.|Theranostics. 2023; 13(6):2040-2056.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, protect from light)
• Clinical Information: No Development Reported