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Desonide (Standard)

CAT: 0804-HY-B0248R-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0248R-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Desonide (Standard) is the analytical standard of Desonide. This product is intended for research and analytical applications. Desonide is a non-fluorinated corticosteroid anti-inflammatory agent that acts on the glucocorticoid receptor. Desonide can also specifically bind to the mutant huntingtin protein (mHTT), reducing the level and toxicity of mHTT. Desonide can be used in the research of Huntington's disease and inflammatory diseases such as atopic dermatitis.
CAS Number
638-94-8
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; Glucocorticoid Receptor; Huntingtin; Reference Standards
Type
Reference Standards
Related Pathways
Apoptosis; Immunology/Inflammation; Neuronal Signaling; Others; Vitamin D Related/Nuclear Receptor
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/desonide-standard.html
Purity
98.63
Smiles
C[C@@]12[C@@]3(C(CO)=O)[C@@](OC(C)(O3)C)([H])C[C@@]1([H])[C@]4([H])CCC5=CC(C=C[C@]5(C)[C@@]4([H])[C@@H](O)C2)=O
Molecular Formula
C24H32O6
Molecular Weight
416.51
Precautions
H302, H315, H319, H335
References & Citations
[1]Kahanek, N., C. Gelbard, and A. Hebert, Desonide: a review of formulations, efficacy and safety. Expert Opin Investig Drugs, 2008. 17 (7) : p. 1097-104.|[2]Castanedo-Cazares, J.P., et al., Topical niacinamide 4% and desonide 0.05% for treatment of axillary hyperpigmentation: a randomized, double-blind, placebo-controlled study. Clin Cosmet Investig Dermatol, 2013. 6: p. 29-36.|[3]Parish, D. and N. Scheinfeld, Desonide foam: a review. Drugs Today (Barc), 2008. 44 (1) : p. 55-62.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards

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