Products for Research Use Only
RegisterLogin

Maurotoxin

CAT: 0804-HY-P5165Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-P5165Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Maurotoxin is a 34-residue and four disulde-bridged toxin that can be isolated from the chactoid scorpion (Scorpio maurus) . Maurotoxin inhibits the Shaker potassium channels (ShB) K+ current with an IC50 of 2 nM[1][2].
CAS Number
188240-41-7
UNSPSC
12352209
Target
Potassium Channel
Type
Peptides
Related Pathways
Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/maurotoxin.html
Solubility
10 mM in DMSO
Smiles
O=C(N[C@@H](CO)C(N[C@@H](CSSC[C@@H](C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(N)=O)C(N[C@@H](CCCCN)C(N[C@H]1CO)=O)=O)=O)=O)NC2=O)C(N[C@@H]([C@H](O)C)C(NCC(N[C@@H](CO)C(N[C@@H](CCCCN)C(N[C@@H](CC(O)=O)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CCCCN)C(N[C@@H](CSSC[C@@H](C(N)=O)NC3=O)C(N[C@@H](CC4=CC=C(C=C4)O)C(NC3)=O)=O)=O)=O)NC1=O)C(N[C@@H](CC5=CC=C(C=C5)O)C(N[C@@H](C)C(N6[C@@H](CCC6)C(N[C@@H](CSSC[C@@H](C(N7[C@@H](CCC7)C(N[C@@H](CC(N)=O)C(N[C@@H](C)C(N[C@H]2CCCCN)=O)=O)=O)=O)NC8=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](CCC(N)=O)C(N[C@@H]([C@H](O)C)C(NC8)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](C(C)C)N
Molecular Formula
C145H232N46O46S8
Molecular Weight
3612.19
References & Citations
[1]Bende NS, et al. A distinct sodium channel voltage-sensor locus determines insect selectivity of the spider toxin Dc1a. Nat Commun. 2014 Jul 11;5:4350.|[2]Castle NA, et al. Maurotoxin: a potent inhibitor of intermediate conductance Ca2+-activated potassium channels. Mol Pharmacol. 2003 Feb;63 (2) :409-18.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

Alternative Products

CatalogName
MBS5821839Maurotoxin

Popular Products