cis-3,4',5-Trimethoxy-3'-hydroxystilbene

• CAS Number:

  586410-08-4

• UNSPSC Description:

  cis-3,4',5-Trimethoxy-3'-hydroxystilbene is a stilbene. cis-3,4',5-Trimethoxy-3'-hydroxystilbene induces cytochrome c release to the cytoplasm. cis-3,4',5-Trimethoxy-3'-hydroxystilbene-induced apoptosis is associated with mitochondrial release of cytochrome c. cis-3,4',5-Trimethoxy-3'-hydroxystilbene also suppresses tubulin polymerization. cis-3,4',5-Trimethoxy-3'-hydroxystilbene can be used for leukemic research[1].

• Target Antigen:

  Apoptosis; Microtubule/Tubulin

• Type:

  Reference compound

• Related Pathways:

  Apoptosis;Cell Cycle/DNA Damage;Cytoskeleton

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/cis-3-4-5-trimethoxy-3-hydroxystilbene.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OC(C=C1/C=C\C2=CC(OC)=CC(OC)=C2)=C(C=C1)OC

• Molecular Weight:

  286.32

• References & Citations:

  [1]Cao TM, et al. Stilbene derivatives that are colchicine-site microtubule inhibitors have antileukemic activity and minimal systemic toxicity. Am J Hematol. 2008 May;83(5):390-7.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported