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3-Hydroxymethyl-β-carboline

CAT: 0804-HY-W197533Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-W197533Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
3-Hydroxymethyl-β-carboline antagonizes the anxiolytic and anticonvulsant actions of Diazepam and reverses the sedative action of Flurazepam. 3-Hydroxymethyl-β-carboline also antagonizes the cerebrovascular and cerebral metabolic depression produced by Flurazepam[1][2].
CAS Number
65474-79-5
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/3-hydroxymethyl-β-carboline.html
Smiles
C1=CC=C2C(=C1)C3=C(C=NC(=C3)CO)N2
Molecular Formula
C12H10N2O
Molecular Weight
198.22
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501
References & Citations
[1]Skolinick P, et al. 3-hydroxymethyl-beta-carboline antagonizes some pharmacologic actions of diazepam. Eur J Pharmacol. 1981 Feb 19;69 (4) :525-7. |[2]Hoffman WE, et al. Cerebrovascular and cerebral metabolic effects of flurazepam and a benzodiazepine antagonist, 3-hydroxymethyl-beta-carboline. Eur J Pharmacol. 1984 Nov 27;106 (3) :585-91.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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