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Clocortolone

CAT: 0804-HY-A0255Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-A0255Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Clocortolone is a synthetic glucocorticoid steroid and corticosteroid ester. Clocortolone can be used for seborrheic dermatitis, contact dermatitis, atopic dermatitis, and psoriasis. Clocortolone has local in vivo potency and is not easily absorbed into systemic circulation[1].
CAS Number
4828-27-7
UNSPSC
12352211
Hazard Statement
H302-H315-H319-H335
Target
Drug Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/clocortolone.html
Smiles
C[C@@]12[C@@H](C(CO)=O)[C@H](C)C[C@@]1([H])[C@]3([H])C[C@H](F)C4=CC(C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C2)=O
Molecular Formula
C22H28ClFO4
Molecular Weight
410.91
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Singh S, et al. Clinical utility of clocortolone pivalate for the treatment of corticosteroid-responsive skin disorders: a systematic review[J]. Clinical, Cosmetic and Investigational Dermatology, 2012: 61-68.|[2]Kircik LH, et al. The treatment of inflammatory facial dermatoses with topical corticosteroids: focus on clocortolone pivalate 0.1% cream. J Drugs Dermatol. 2012 Oct;11 (10) :1194-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched

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