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Levetiracetam

CAT: 0804-HY-B0106-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0106-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Levetiracetam, an antiepileptic agent, binds the synaptic vesicle protein SV2A. Levetiracetam enhances Temozolomide effect on glioblastoma stem cell proliferation and apoptosis. Levetiracetam modulates HDAC levels ultimately silencing MGMT, thus increasing Temozolomide effectiveness. A chemosensitizer agent[1][2].
CAS Number
102767-28-2
Product Name Alternative
UCB L059
UNSPSC
12352005
Hazard Statement
H302, H319
Target
DNA Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Neuroscience-Neuromodulation
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/levetiracetam.html
Purity
99.98
Solubility
DMSO : ≥ 85 mg/mL|H2O : ≥ 85 mg/mL
Smiles
NC([C@@H](N(CCC1)C1=O)CC)=O
Molecular Formula
C8H14N2O2
Molecular Weight
170.21
Precautions
H302, H319
References & Citations
[1]Bianca Maria Scicchitano, et al. Levetiracetam enhances the temozolomide effect on glioblastoma stem cell proliferation and apoptosis. Cancer Cell Int. 2018 Sep 10;18:136.|[2]Delia M Talos, et al. Antiepileptic effects of levetiracetam in a rodent neonatal seizure model. Pediatr Res. 2013 Jan;73 (1) :24-30.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched

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