Fenvalerate

• UNSPSC Description:

  Fenvalerate is a potent protein phosphatase 2B (calcineurin) inhibitor with an IC50 of 2-4 nM for PP2B-Aα. Fenvalerate is a pyrethroid ester insecticide and acaricide[1].

• Target Antigen:

  Bacterial; Phosphatase

• Type:

  Reference compound

• Related Pathways:

  Anti-infection;Metabolic Enzyme/Protease

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/fenvalerate.html

• Purity:

  99.58

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C(OC(C#N)C1=CC=CC(OC2=CC=CC=C2)=C1)C(C(C)C)C3=CC=C(Cl)C=C3

• Molecular Weight:

  419.90

• References & Citations:

  [1]E Enan, et al. Specific Inhibition of Calcineurin by Type II Synthetic Pyrethroid Insecticides. Biochem Pharmacol. 1992 Apr 15;43(8):1777-84.|[2]A R Reilein, et al. Regulation of Organelle Movement in Melanophores by Protein Kinase A (PKA), Protein Kinase C (PKC), and Protein Phosphatase 2A (PP2A). J Cell Biol. 1998 Aug 10;142(3):803-13.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  51630-58-1