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J5 peptide

CAT: 0804-HY-P3248Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-P3248Size:1 Each
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Description
J5 peptide is an MBP inhibitor that competitively inhibits the binding of MBP85-99 to HLA-DR2. J5 peptide alleviates PLP139-151/MBP85-99-induced experimental autoimmune encephalomyelitis (EAE) in mice. J5 peptide can be used in research on inflammatory and immune diseases[1].
CAS Number
444305-16-2
Product Name Alternative
Myelin basic protein (85-99) antagonist
UNSPSC
12352209
Target
Biochemical Assay Reagents
Type
Peptides
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/j5-peptide.html
Solubility
10 mM in DMSO
Smiles
OC(CC[C@H](N)C(N[C@@H](CCCCN)C(N1[C@@H](CCC1)C(N[C@@H](CCCCN)C(N[C@@H](C(C)C)C(N[C@@H](CCC(O)=O)C(N[C@@H](C)C(N[C@H](C(N[C@@H](CCCCN)C(N[C@@H](C)C(N[C@@H](C)C(N[C@@H](C)C(N[C@@H](C)C(N2[C@@H](CCC2)C(N[C@@H](C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)CC3=CC=C(C=C3)O)=O)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C70H114N18O21
Molecular Weight
1543.76
References & Citations
[1]Smith CE, et al. Differential induction of IgE-mediated anaphylaxis after soluble vs. cell-bound tolerogenic peptide therapy of autoimmune encephalomyelitis. Proc Natl Acad Sci U S A. 2005 Jul 5;102 (27) :9595-600.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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