DL-dithiothreitol

• Description :

  DL-dithiothreitol (DTT) is a strong reductant with anti-disulfidptosis activity. When DL-dithiothreitol is oxidized, it forms a stable six-membered ring with an internal disulfide bond[1][2].

• Product Name Alternative :

  DTT; rel- (2R,3R) -1,4-Dimercapto-2,3-butanediol

• UNSPSC :

  12352200

• Hazard Statement :

  H302, H315, H318, H402

• Target :

  Biochemical Assay Reagents; Disulfidptosis

• Type :

  Biochemical Assay Reagents

• Related Pathways :

  Others

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/DTT.html

• Concentration :

  10mM

• Purity :

  99.8

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  SC[C@@H](O)[C@H](O)CS

• Molecular Formula :

  C4H10O2S2

• Molecular Weight :

  154.25

• Precautions :

  H302, H315, H318, H402

• References & Citations :

  [1]Dithiothreitol, From Wikipedia|[2]Yao H, et al. Establishment of disulfidptosis-related LncRNA signature as biomarkers in colon adenocarcinoma[J]. Cancer Cell International, 2024, 24 (1) : 183.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, protect from light, stored under nitrogen)

• Scientific Category :

  Biochemical Assay Reagents

• Clinical Information :

  No Development Reported

• CAS Number :

  [3483-12-3]