Products for Research Use Only
RegisterLogin

SR10067

CAT: 0804-HY-117516-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-117516-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
SR10067 is a potent, selective and brain penetrant REV-ERB agonist. SR10067 has high affinity for Rev-Erbβ and Rev-Erbα with IC50 values of 160 nM and 170 nM, respectively. SR10067 can be used for the research of metabolic diseases and neuropsychiatric disorders[1][2].
CAS Number
1380548-02-6
UNSPSC
12352005
Target
REV-ERB
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Neuroscience-Neuromodulation
Field of Research
Metabolic Disease; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/sr10067.html
Purity
99.21
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(OC1=CC=C(OCC2CC3=CC=CC=C3CN2C(C4=CC=CC5=C4C=CC=C5)=O)C=C1)(C)C
Molecular Formula
C31H31NO3
Molecular Weight
465.58
References & Citations
[1]Banerjee S, et al. Pharmacological targeting of the mammalian clock regulates sleep architecture and emotional behaviour. Nat Commun. 2014 Dec 23;5:5759. doi: 10.1038/ncomms6759.|[2]Thevis M, et al. Emerging drugs affecting skeletal muscle function and mitochondrial biogenesis - Potential implications for sports drug testing programs. Rapid Commun Mass Spectrom. 2016 Mar 15;30 (5) :635-51.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-139691-01SR15006
HY-13421-01SR1001
HY-13421R-01SR1001 (Standard)

Alternative Products

CatalogName
FFC54802-01SR10067
A18671-25SR10067 25mg
A18671-200SR10067 200mg
A18671-100SR10067 100mg
A18671-50SR10067 50mg
A18671-1SR10067 1mg
A18671-10SR10067 10mg
A18671-5SR10067 5mg
A18671-10mM-DSR10067 10mM * 1mL in DMSO
bs-60240C-01SR10067 --- REV-ERB Agonist

Popular Products