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Recombinant Human CYP51A1

CAT: 0710-P2716-01Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0710-P2716-01Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Product Name Alternative
CP51, CYP51, CYP51A1, CYPL1, CYPLI, Cytochrome P450 14DM, Cytochrome P450 51A1, Cytochrome P45014DM, Cytochrome P450LI, LDM, P450 14DM, P450L1, Sterol 14 alpha demethylase
UniProt
Q16850
Expression Region
290-503
Host
E.Coli
Tag
N-terminal His-IF2DI Tag
Applications
Western Blot, ELISA
Field of Research
Metabolism
Purity
Greater than 90% as determined by SDS-PAGE.
Form
Lyophilized powder
Reconstitution
Centrifuge the vial before opening, reconstitute in sterile distilled water to a concentration of 0.1-1 mg/ml by gently pipetting 2-3 times, don't vortex.
Molecular Weight
45.3 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
The lyophilized protein is stable at -20 °C for up to 1 year. For extended storage, it is recommended to further dilute in working aliquots after reconstitution. The protein solution is stable at ≤ -20 °C for 3 months, or 2-7 days at 2-8 °C under sterile conditions.Avoid repeated freeze/thaw cycle.
Formulation
Lyophilized from a 0.2 μm filtered solution of 10 mM Hepes, 150 mM NaCl with 5% trehalose, pH 7.4.
Organism Species
Human

UniProtKB · Q16850

Lanosterol 14-alpha demethylase

CP51A_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q16850
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CYP51A1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
LDM
EC number
1.14.14.154
Processing
—
Secondary accessions
A0A0C4DFL7, A4D1F8, B2RAI4, B4DJ55, O00770, O00772, Q16784, Q8N1A8, Q99868
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

Cholesterol biosynthesisCholesterol metabolismLipid biosynthesisLipid metabolismSteroid biosynthesisSteroid metabolismSterol biosynthesisSterol metabolism

Cellular component

Endoplasmic reticulumMembraneMicrosome

Ligand

HemeIronMetal-binding

Molecular function

MonooxygenaseOxidoreductase

Domain

TransmembraneTransmembrane helix

PTM

Ubl conjugation

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