HMG-CoA

• Description:

  HMG-CoA is a product generated by the hydration reaction of (E) -3-methylglutaconyl-CoA (MG-CoA) catalyzed by methylglutaconyl-CoA hydratase (MGCH) [1].

• Product Name Alternative:

  3-Hydroxy-3-methylglutaryl-CoA

• UNSPSC:

  12352204

• Target:

  Acetyl-CoA synthetase

• Type:

  Enzyme

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/hmg-coa.html

• Solubility:

  10 mM in DMSO

• Smiles:

  NC1=NC=NC2=C1N=CN2[C@H]3[C@H](O)[C@H](OP(O)(O)=O)[C@@H](COP(O)(OP(O)(OCC(C)([C@H](C(NCCC(NCCSC(CC(C)(CC(O)=O)O)=O)=O)=O)O)C)=O)=O)O3

• Molecular Formula:

  C27H44N7O20P3S

• Molecular Weight:

  911.66

• References & Citations:

  [1]Brian J Wong, et al. Evolution of function in the crotonase superfamily: (3S) -methylglutaconyl-CoA hydratase from Pseudomonas putida. Biochemistry. 2004 Apr 27;43 (16) :4646-54.|[2]Wong BJ, et al. Evolution of function in the crotonase superfamily: (3S) -methylglutaconyl-CoA hydratase from Pseudomonas putida. Biochemistry. 2004 Apr 27;43 (16) :4646-54.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Enzyme

• Clinical Information:

  Phase 4

• CAS Number:

  1553-55-5