HMG-CoA

• UNSPSC Description:

  HMG-CoA is a product generated by the hydration reaction of (E)-3-methylglutaconyl-CoA (MG-CoA) catalyzed by methylglutaconyl-CoA hydratase (MGCH)[1].

• Target Antigen:

  Others

• Type:

  Enzyme

• Related Pathways:

  Others

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/hmg-coa.html

• Solubility:

  10 mM in DMSO

• Smiles:

  NC1=NC=NC2=C1N=CN2[C@H]3[C@H](O)[C@H](OP(O)(O)=O)[C@@H](COP(O)(OP(O)(OCC(C)([C@H](C(NCCC(NCCSC(CC(C)(CC(O)=O)O)=O)=O)=O)O)C)=O)=O)O3

• Molecular Weight:

  911.66

• References & Citations:

  [1]Brian J Wong, et al. Evolution of function in the crotonase superfamily: (3S)-methylglutaconyl-CoA hydratase from Pseudomonas putida. Biochemistry. 2004 Apr 27;43(16):4646-54.|[2]Wong BJ, et al. Evolution of function in the crotonase superfamily: (3S)-methylglutaconyl-CoA hydratase from Pseudomonas putida. Biochemistry. 2004 Apr 27;43(16):4646-54.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  Phase 4

• CAS Number:

  1553-55-5