c-Myb (Acetyl Lys480) rabbit pAb

c-Myb (Acetyl Lys480) rabbit pAb

• Description: Domain: Comprised of 3 domains; an N-terminal DNA-binding domain, a centrally located transcriptional activation domain and a C-terminal domain involved in transcriptional repression. function: Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells. PTM: Phosphorylated by NLK on multiple sites, which induces proteasomal degradation. PTM: Ubiquitinated; mediated by SIAH1 and leading to its subsequent proteasomal degradation. similarity: Contains 3 HTH myb-type DNA-binding domains. subunit: Binds MYBBP1A. Interacts with HIPK2, MAF and NLK.
• Synonyms: Transcriptional activator Myb (Proto-oncogene c-Myb)
• Gene ID: 4602
• UniProt: P10242
• Cellular Locus: Nucleus.
• Host: Rabbit
• Species Reactivity: Human, Mouse
• Immunogen: Synthesized peptide derived from human c-Myb (Acetyl Lys480)
• Clonality: Polyclonal
• Validated Applications: WB, ELISA
• Stability: 1 year
• Concentration: 1 mg/mL
• Dilution: WB 1:1000-2000 ELISA 1:5000-20000
• Molecular Weight: 70kD
• Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.