Sakurasosaponin

CAT: 0804-HY-N7459Size: InquireDry Ice: NoHazardous: No

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CAT#:0804-HY-N7459Size:Inquire

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

59527-84-3

UNSPSC Description

Sakurasosaponin is a saponin with potential anticancer activity that can be extracted from the root of Primula sieboldii. Sakurasosaponin can activate the AMPK pathway to induce cell autophagy and exert anti-NSCLC cell proliferation activity. Sakurasosaponin also has antifungal activity and significantly inhibits the growth of anthrax.

Target Antigen

AMPK; Autophagy; Fungal

Type

Natural Products

Related Pathways

Anti-infection;Autophagy;Epigenetics;PI3K/Akt/mTOR

Field of Research

cancer

Assay Protocol

https://www.medchemexpress.com/sakurasosaponin.html

Smiles

C[C@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@H](O[C@@H]2[C@H](O)[C@@H](O)[C@H](C)O[C@H]2O[C@@H]3[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]3O[C@H]4[C@H](O)[C@@H](O[C@H]5[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O5)[C@H](O[C@H]6CC[C@]7(C)C8CC[C@@]9%10C%11CC(C)(C)CCC%11([C@H](O)C[C@@]%10(C)[C@]8(C)CCC7C6(C)C)CO9)O[C@@H]4C(O)=O)O1

Molecular Weight

1251.40

References & Citations

[1]Seo Y, Lim C, Lee J, Kim J, Kim YH, Lee PCW, Jang SW. Sakurasosaponin inhibits lung cancer cell proliferation by inducing autophagy via AMPK activation. Oncol Lett. 2023 Oct 5;26(6):501.|[2]García-Sosa K, et al. Antifungal activity of sakurasosaponin from the root extract of Jacquinia flammea. Nat Prod Res. 2011 Jul;25(12):1185-9.

Shipping Conditions

Room temperature

Clinical Information

No Development Reported

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