1,1-Dimethylethyl 4-(4-amino-3-pyridinyl)-1-piperazinecarboxylate

• UNSPSC Description:

  1,1-Dimethylethyl 4-(4-amino-3-pyridinyl)-1-piperazinecarboxylate is the impurity of Palbociclib (HY-50767). Palbociclib is an orally active selective CDK4 and CDK6 inhibitor with IC50 values of 11 and 16 nM, respectively[1].

• Target Antigen:

  CDK

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/1-1-dimethylethyl-4-4-amino-3-pyridinyl-1-piperazinecarboxylate.html

• Purity:

  99.92

• Smiles:

  O=C(N1CCN(C2=C(N)C=CN=C2)CC1)OC(C)(C)C

• Molecular Weight:

  278.36

• References & Citations:

  [1]Fry DW, et al. Specific inhibition of cyclin-dependent kinase 4/6 by PD 0332991 and associated antitumor activity in human tumor xenografts. Mol Cancer Ther. 2004 Nov;3(11):1427-38.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Clinical Information:

  No Development Reported

• CAS Number:

  1023594-50-4