Biotin-PEG4-dialkoxydiphenylsilane-picolyl azide

Biotin-PEG4-dialkoxydiphenylsilane-picolyl azide

• CAS Number: 2599839-59-3
• UNSPSC Description: Biotin-PEG4-dialkoxydiphenylsilane-picolyl azide is a clickable, acid-cleavable biotin-picolyl azide. Biotin-PEG4-dialkoxydiphenylsilane-picolyl azide is an enrichment handle of cell surface glycoproteins for protein labeling[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
• Target Antigen: Fluorescent Dye
• Type: Dye Reagents
• Related Pathways: Others
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/biotin-peg4-dialkoxydiphenylsilane-picolyl-azide.html
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: O=C(N1)N[C@](CS2)([H])[C@@]1([H])[C@@H]2CCCCC(NCCOCCOCCOCCOCCC(NCC(C)(C)O[Si](C3=CC=CC=C3)(C4=CC=CC=C4)OCCCNC(C5=CN=C(CN=[N+]=[N-])C=C5)=O)=O)=O
• Molecular Weight: 978.24
• References & Citations: [1]Benjamin Schumann, et al. Bump-and-Hole Engineering Identifies Specific Substrates of Glycosyltransferases in Living Cells. Mol Cell. 2020 Jun 4;78(5):824-834.e15.
• Shipping Conditions: Blue Ice
• Clinical Information: No Development Reported