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DCPT1061

CAT: 0804-HY-162003-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-162003-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DCPT1061 potently inhibits PRMT1, PRMT6 and PRMT8 in vitro with less inhibitory effect on PRMT3, PRMT4, and PRMT5 or other epigenetic enzymes. DCPT1061 has antitumor effect[1][2].
CAS Number
2289726-31-2
UNSPSC
12352005
Target
Histone Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dcpt1061.html
Purity
99.81
Solubility
DMSO : ≥ 250 mg/mL
Smiles
ClC1=C(OC2=CC=CC=C2CN(C)CCNC)C=CC=C1Cl
Molecular Formula
C17H20Cl2N2O
Molecular Weight
339.26
References & Citations
[1]Jianfeng Wang, et al. PRMT1 is a novel molecular therapeutic target for clear cell renal cell carcinoma. Theranostics. 2021 Mar 12;11 (11) :5387-5403.|[2]Hongru Tao, et al. PRMT1 inhibition activates the interferon pathway to potentiate antitumor immunity and enhance checkpoint blockade efficacy in melanoma. Cancer Res. 2023 Nov 22.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
BA4883-10DCPT1061

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