Fallypride precursor

• UNSPSC Description:

  Fallypride precursor (Compound 15) can be used for synthesis of Fallypride (HY-135497). Fallypride is an antagonist of the dopamine D2/D3 receptor. Fallypride can be used as a positron emission tomography (PET) radiotracer when labeled with 18F[1].

• Target Antigen:

  Dopamine Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/fallypride-precursor.html

• Solubility:

  DMSO : 200 mg/mL (ultrasonic)

• Smiles:

  C=CCN(CCC1)[C@@H]1CNC(C2=C(C(OC)=CC(CCCOS(=O)(C3=CC=C(C=C3)C)=O)=C2)OC)=O

• Molecular Weight:

  516.65

• References & Citations:

  [1]Mukherjee J, et al., Fluorinated benzamide neuroleptics--III. Development of (S)-N-[(1-allyl-2-pyrrolidinyl)methyl]-5-(3-[18F]fluoropropyl)-2, 3-dimethoxybenzamide as an improved dopamine D-2 receptor tracer. Nucl Med Biol. 1995 Apr;22(3):283-96.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  166173-74-6