Glycolate oxidase-IN-1

Glycolate oxidase-IN-1

• CAS Number: 330977-65-6
• UNSPSC Description: Glycolate oxidase-IN-1(compound 26), a salicylic acid derivative, is a glycolate oxidase (GO) inhibitor with an IC50 of 38.2 μM. Glycolate oxidase-IN-1 has the ability to reduce oxalate production in hyperoxalate hepatocytes and can be used in the study of primary hyperoxaluria type 1 (PH1)[1].
• Target Antigen: Others
• Type: Reference compound
• Related Pathways: Others
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/glycolate-oxidase-in-1.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(O)C1=CC(C2=CC=C(C=O)O2)=CC=C1O
• Molecular Weight: 232.19
• References & Citations: [1]María Dolores Moya-Garzón, et al. Salicylic Acid Derivatives Inhibit Oxalate Production in Mouse Hepatocytes with Primary Hyperoxaluria Type 1. J Med Chem. 2018 Aug 23;61(16):7144-7167.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported