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Beloxepin

CAT: 0804-HY-106407Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-106407Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Beloxepin (Org 4428) is an orally active synaptosomal noradrenalin reuptake inhibitor and a 5-HT2 receptor antagonist. Beloxepin shows about 100-fold less affine for other monoamine carriers. Beloxepin has antidepressant and pain-relieving effects[1][2].
CAS Number
135928-30-2
Product Name Alternative
Org 4428; ADL 6906
UNSPSC
12352005
Hazard Statement
H302, H312, H317, H332, H334
Target
5-HT Receptor; Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/beloxepin.html
Purity
98.04
Smiles
O[C@@]12[C@@](CN(CC2)C)([H])C3=CC=CC(C)=C3OC4=CC=CC=C41
Molecular Formula
C19H21NO2
Molecular Weight
295.38
Precautions
H302, H312, H317, H332, H334
References & Citations
[1]Lorenzo Di Cesare Mannelli, et al. α2 Adrenoceptor: a Target for Neuropathic Pain Treatment. Mini Rev Med Chem. 2017;17 (2) :95-107.|[2]Craig T Hartrick. Noradrenergic reuptake inhibition in the treatment of pain. Expert Opin Investig Drugs. 2012 Dec;21 (12) :1827-34.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
α-1 microglobulin

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CatalogName
T26765-01Beloxepin

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