Benzoin

• Description:

  Benzoin (DL-Benzoin), a natural balsamic resin, is a PI3Kα inhibitor with anticancer effects. Benzoin inihits the growth of colon cancer cell line (HCT-116) . Benzoin can be used as a food additive[1][2].

• Product Name Alternative:

  DL-Benzoin; Desyl alcohol; (±) -2-Hydroxy-2-phenylacetophenone

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  PI3K

• Type:

  Natural Products

• Related Pathways:

  PI3K/Akt/mTOR

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/benzoin.html

• Purity:

  99.95

• Solubility:

  DMSO : 50 mg/mL (ultrasonic)

• Smiles:

  OC(C1=CC=CC=C1)C(C2=CC=CC=C2)=O

• Molecular Formula:

  C14H12O2

• Molecular Weight:

  212.25

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]John JW Coppen, et al. Benzoin: Production, Uses and International Trade. Apr 6th, 2016.|[2]Sabbah DA, et al. Molecular modeling based approach, synthesis, and cytotoxic activity of novel benzoin derivatives targeting phosphoinostide 3-kinase (PI3Kα) . Bioorg Med Chem Lett. 2015 Aug 15;25 (16) :3120-4.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  Store at room temperature 3 years

• Scientific Category:

  Natural Products

• Clinical Information:

  Launched

• CAS Number:

  [119-53-9]