Benzoin

• Description :

  Benzoin (DL-Benzoin), a natural balsamic resin, is a PI3Kα inhibitor with anticancer effects. Benzoin inihits the growth of colon cancer cell line (HCT-116) . Benzoin can be used as a food additive[1][2].

• Product Name Alternative :

  DL-Benzoin; Desyl alcohol; (±) -2-Hydroxy-2-phenylacetophenone

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  PI3K

• Type :

  Natural Products

• Related Pathways :

  PI3K/Akt/mTOR

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/benzoin.html

• Purity :

  99.95

• Solubility :

  DMSO : 50 mg/mL (ultrasonic)

• Smiles :

  OC(C1=CC=CC=C1)C(C2=CC=CC=C2)=O

• Molecular Formula :

  C14H12O2

• Molecular Weight :

  212.25

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]John JW Coppen, et al. Benzoin: Production, Uses and International Trade. Apr 6th, 2016.|[2]Sabbah DA, et al. Molecular modeling based approach, synthesis, and cytotoxic activity of novel benzoin derivatives targeting phosphoinostide 3-kinase (PI3Kα) . Bioorg Med Chem Lett. 2015 Aug 15;25 (16) :3120-4.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  Store at room temperature 3 years

• Scientific Category :

  Natural Products

• Clinical Information :

  Launched

• CAS Number :

  [119-53-9]