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Asperbisabolane L

CAT: 0804-HY-N10458Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-N10458Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Asperbisabolane L, a sesquiterpenoid, exerts the anti-inflammatory activity by inhibiting the NF-κB-activated pathway. Asperbisabolane L inhibits the translocation of NF-κB from cytoplasm to the nucleus. Asperbisabolane L also inhibits NO production in LPS-activated BV-2 microglia cells[1].
UNSPSC
12352005
Target
NF-κB
Type
Natural Products
Related Pathways
NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/asperbisabolane-l.html
Solubility
10 mM in DMSO
Smiles
OC1=CC(C)=CC=C1/C(C)=C\CC(O)=O
Molecular Formula
C12H14O3
Molecular Weight
206.24
References & Citations
[1]Siwen Niu, et al. Phenolic bisabolane and cuparene sesquiterpenoids with anti-inflammatory activities from the deep-sea-derived Aspergillus sydowii MCCC 3A00324 fungus. Bioorg Chem.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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