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Gosuranemab

CAT: 0804-HY-P99648-01Size: 1 mgDry Ice: YesHazardous: No
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CAT#:0804-HY-P99648-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Gosuranemab (BMS-986168; IPN007) is a humanised IgG4 anti-tau monoclonal antibody. Gosuranemab neutralizes the extracellular tau protein, inhibiting the spread and aggregation of pathological tau protein. Gosuranemab can be used for the researches of alzheimer’s disease (AD) and progressive supranuclear palsy (PSP) [1][2].
CAS Number
1788032-39-2
Product Name Alternative
BMS-986168; IPN007; BIIB092
UNSPSC
12352203
Target
Tau Protein
Type
Inhibitory Antibodies
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/gosuranemab.html
Purity
97.31
Solubility
10 mM in DMSO
Smiles
[Gosuranemab]
Molecular Weight
(144.94 kDa)
References & Citations
[1]Song C, et al. Immunotherapy for Alzheimer's disease: targeting β-amyloid and beyond. Transl Neurodegener. 2022 Mar 18;11 (1) :18.|[2]Imbimbo BP, et al. A critical appraisal of tau-targeting therapies for primary and secondary tauopathies. Alzheimers Dement. 2022 May;18 (5) :1008-1037.|[3]Qureshi IA, et al. A randomized, single ascending dose study of intravenous BIIB092 in healthy participants. Alzheimers Dement (N Y) . 2018 Dec 17;4:746-755.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 1

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