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WAY-361789

CAT: 0804-HY-18039Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-18039Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
WAY-361789 (SEN15924) is an orally active agonist for α7 nicotinic acetylcholine receptor (α7 nAChR) with an EC50 of 0.18 μM. WAY-361789 improves the cognitive function, exhibits potential in ameliorating Alzheimer’s Disease and schizophrenia[1].
CAS Number
1040718-40-8
Product Name Alternative
SEN15924
UNSPSC
12352005
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/way-361789.html
Smiles
O=C(NC1=NNC(C2=CC=C(OC)C=C2)=C1)CCCCN3CCN(C(C)=O)CCC3
Molecular Formula
C22H31N5O3
Molecular Weight
413.51
References & Citations
[1]Zanaletti R, et al. Discovery of a novel alpha-7 nicotinic acetylcholine receptor agonist series and characterization of the potent, selective, and orally efficacious agonist 5- (4-acetyl[1,4]diazepan-1-yl) pentanoic acid [5- (4-methoxyphenyl) -1H-pyrazol-3-yl] amide (SEN15924, WAY-361789) . J Med Chem. 2012 May 24;55 (10) :4806-23.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AChE

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