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Pogostone

CAT: 0804-HY-N1416-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N1416-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Pogostone is isolated from patchouli oil with anti-bacterial and anti-cancer activities. Pogostone inhibits both gram negative and gram positive bacteria, also show inhibitory effect on corynebacterium xerosis with a MIC value of 0.098 µg/ml [2]. Pogostone induces cell apoptosis and autophagy[2].
CAS Number
23800-56-8
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; Autophagy; Bacterial
Type
Natural Products
Related Pathways
Anti-infection; Apoptosis; Autophagy
Applications
Cancer-programmed cell death
Field of Research
Infection; Inflammation/Immunology; Cancer
Assay Protocol
https://www.medchemexpress.com/pogostone.html
Purity
99.81
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1C(C(CCC(C)C)=O)=C(O)C=C(C)O1
Molecular Formula
C12H16O4
Molecular Weight
224.25
Precautions
H302, H315, H319, H335
References & Citations
[1]Peng F, et al. In vitro and in vivo antibacterial activity of Pogostone.Chin Med J (Engl) . 2014;127 (23) :4001-5.|[2]Cao ZX, et al. Pogostone induces autophagy and apoptosis involving PI3K/Akt/mTOR axis in human colorectal carcinoma HCT116 cells.J Ethnopharmacol. 2017 Apr 18;202:20-27.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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