Pogostone

• Description :

  Pogostone is isolated from patchouli oil with anti-bacterial and anti-cancer activities. Pogostone inhibits both gram negative and gram positive bacteria, also show inhibitory effect on corynebacterium xerosis with a MIC value of 0.098 µg/ml [2]. Pogostone induces cell apoptosis and autophagy[2].

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Apoptosis; Autophagy; Bacterial

• Type :

  Natural Products

• Related Pathways :

  Anti-infection; Apoptosis; Autophagy

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Infection; Inflammation/Immunology; Cancer

• Assay Protocol :

  https://www.medchemexpress.com/pogostone.html

• Purity :

  99.81

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  O=C1C(C(CCC(C)C)=O)=C(O)C=C(C)O1

• Molecular Formula :

  C12H16O4

• Molecular Weight :

  224.25

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Peng F, et al. In vitro and in vivo antibacterial activity of Pogostone.Chin Med J (Engl) . 2014;127 (23) :4001-5.|[2]Cao ZX, et al. Pogostone induces autophagy and apoptosis involving PI3K/Akt/mTOR axis in human colorectal carcinoma HCT116 cells.J Ethnopharmacol. 2017 Apr 18;202:20-27.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, protect from light)

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• CAS Number :

  [23800-56-8]