Ceforanide

• Description:

  Ceforanide is a semisynthetic parental cephalosporin antibiotic, derived from 7-aminocephalosporanic acid. Ceforanide has antibacterial activity and is a potent inhibitor of most species of streptococci, excluding enterococci[1][2].

• UNSPSC:

  12352005

• Hazard Statement:

  H317, H334

• Target:

  Antibiotic; Bacterial

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/ceforanide.html

• Purity:

  99.23

• Solubility:

  DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles:

  O=C(C(N12)=C(CSC3=NN=NN3CC(O)=O)CS[C@]2([H])[C@H](NC(CC4=CC=CC=C4CN)=O)C1=O)O

• Molecular Formula:

  C20H21N7O6S2

• Molecular Weight:

  519.55

• Precautions:

  H317, H334

• References & Citations:

  [1]Campoli-Richards DM, et al. Ceforanide. A review of its antibacterial activity, pharmacokinetic properties and clinical efficacy. Drugs. 1987 Oct;34 (4) :411-37.|[2]Burch, K. H., et al., (1979) . Ceforanide: in vitro and clinical evaluation. Antimicrobial agents and chemotherapy, 16 (3), 386–391.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, sealed storage, away from moisture)

• Scientific Category:

  Reference compound1

• Clinical Information:

  Launched

• Isoform:

  β-lactam

• CAS Number:

  [60925-61-3]