7-Hydroxy-3,4-dihydro-2(1H)-quinolinone

• UNSPSC Description:

  7-?Hydroxy-?3,?4-?dihydro-?2(1H)?-?quinolinone (3,4-Dihydro-7-hydroxy-2(1H)-quinolinone) is a weak MAO-A inhibitor, with an IC50 of 183 μM, and has no effect on MAO-B[1].

• Target Antigen:

  Monoamine Oxidase

• Type:

  Reference compound

• Related Pathways:

  Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/7-​Hydroxy-​3,​4-​dihydro-​2_1H_​-​quinolinone.html

• Purity:

  99.96

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)|H2O : 1 mg/mL (ultrasonic)

• Smiles:

  O=C1NC2=C(C=CC(O)=C2)CC1

• Molecular Weight:

  163.176

• References & Citations:

  [1]Meiring L, et al. Inhibition of monoamine oxidase by 3,4-dihydro-2(1H)-quinolinone derivatives. Bioorg Med Chem Lett. 2013 Oct 15;23(20):5498-502.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  22246-18-0