Phospho-CrkL (Tyr207) Rabbit APC Conjugate

• Description:

  Phospho-CrkL (Tyr207) Rabbit APC Conjugate _x000D_ Catalog number: B2018811_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 10 Tests_x000D_ Molecular Weight or Concentration: N/A_x000D_ Supplied as: Solution_x000D_ Applications: a molecular tool for various biochemical applications_x000D_ Storage: 2-8°C_x000D_ Keywords: Crk-like protein; CRKL; v-crk sarcoma virus CT10 oncogene homolog (avian)-like_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Box CVJ, Sandhu AK, Turaihi AH, Xiaoké P, Dallinga-Thie G, Aman J, Eringa EC. Effects of imatinib on vascular insulin sensitivity and free fatty acid transport in early weight gain PLoS One. 2021 Jul 2;16(7):e0250442._x000D_ 2: Pham TH, Gao X, Singh G, Hardwidge PR. Escherichia coli virulence protein NleH1 interaction with the v-Crk sarcoma virus CT10 oncogene-like protein (CRKL) governs NleH1 inhibition of the ribosomal protein S3 (RPS3)/nuclear factor κB (NF-κB) pathway J Biol Chem. 2013 Nov 29;288(48):34567-74._x000D_ 3: La Rosée P, Holm-Eriksen S, Konig H, Härtel N, Ernst T, Debatin J, Mueller MC, Erben P, Binckebanck A, Wunderle L, Shou Y, Dugan M, Hehlmann R, Ottmann OG, Hochhaus A. Phospho-CRKL monitoring for the assessment of BCR-ABL activity in imatinib-resistant chronic myeloid leukemia or Ph+ acute lymphoblastic leukemia patients treated with nilotinib Haematologica. 2008 May;93(5):765-9._x000D_ 4: Scopim-Ribeiro R, Machado-Neto JA, Eide CA, Coelho-Silva JL, Fenerich BA, Fernandes JC, Scheucher PS, Savage Stevens SL, de Melo Campos P, Olalla Saad ST, de Carvalho Palma L, de Figueiredo-Pontes LL, Simões BP, Rego EM, Tognon CE, Druker BJ, Traina F. NT157, an IGF1R-IRS1/2 inhibitor, exhibits antineoplastic effects in pre-clinical models of chronic myeloid leukemia Invest New Drugs. 2021 Jun;39(3):736-746._x000D_ 5: Kong Y, Wu YL, Song Y, Shi MM, Cao XN, Zhao HY, Qin YZ, Lai YY, Jiang H, Jiang Q, Huang XJ. Ruxolitinib/nilotinib cotreatment inhibits leukemia-propagating cells in Philadelphia chromosome-positive ALL J Transl Med. 2017 Aug 30;15(1):184._x000D_ 6: Luo FR, Yang Z, Camuso A, Smykla R, McGlinchey K, Fager K, Flefleh C, Castaneda S, Inigo I, Kan D, Wen ML, Kramer R, Blackwood-Chirchir A, Lee FY. Dasatinib (BMS-354825) pharmacokinetics and pharmacodynamic biomarkers in animal models predict optimal clinical exposure Clin Cancer Res. 2006 Dec 1;12(23):7180-6._x000D_ 7: Guerrouahen BS, Wieder E, Blanchard EG, Lee FY, Aplenc R, Corey SJ. Flow cytometric determination of Src phosphorylation in pediatric patients treated with dasatinib Pediatr Blood Cancer. 2009 Dec;53(6):1132-5._x000D_ 8: Lickliter JD, Taylor K, Szer J, Grigg A, Arthur C, Hughes TP, Durrant S, Filshie R, Irving I, Seldon M, Ellacott J, Boyd AW, D'Rozario J, Rooney K, Lynch K, Bradstock K; Australasian Leukaemia and Lymphoma Group. An imatinib-only window followed by imatinib and chemotherapy for Philadelphia chromosome-positive acute leukemia: long-term results of the CMLALL1 trial Leuk Lymphoma. 2015 Mar;56(3):630-8._x000D_ 9: Cai J, Wu G, Tan X, Han Y, Chen C, Li C, Wang N, Zou X, Chen X, Zhou F, He D, Zhou L, Jose PA, Zeng C. Transferred BCR/ABL DNA from K562 extracellular vesicles causes chronic myeloid leukemia in immunodeficient mice PLoS One. 2014 Aug 18;9(8):e105200._x000D_ 10: Simara P, Stejskal S, Koutna I, Potesil D, Tesarova L, Potesilova M, Zdrahal Z, Mayer J. Apoptosis in chronic myeloid leukemia cells transiently treated with imatinib or dasatinib is caused by residual BCR-ABL kinase inhibition Am J Hematol. 2013 May;88(5):385-93. _x000D_ _x000D_ Products Related to Phospho-CrkL (Tyr207) Rabbit APC Conjugate can be found at Conjugates

• Short Description:

  Catalog Number: B2018811 (10 Tests)_x000D_ Phospho-CrkL (Tyr207) Rabbit APC Conjugate is an antibody used in research to detect phosphorylated CrkL at tyrosine 207. It helps study CrkL's role in signaling pathways. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request._x000D_ _x000D_

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height :

  0.5