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ARP101

CAT: 0804-HY-101535-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-101535-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ARP101 is a potent and selective inhibitor matrix metalloproteinase-2 (MMP-2) . ARP101 induces autophagy-associated cell death in cancer cells. ARP101 is effective in inducing the formation of autophagosome and conversion of LC3I into LC3II[1].
CAS Number
849773-63-3
UNSPSC
12352005
Target
Atg8/LC3; MMP
Type
Reference compound
Related Pathways
Autophagy; Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/arp101.html
Purity
99.39
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 80°C)
Smiles
CC(C)[C@@H](N(S(=O)(C1=CC=C(C2=CC=CC=C2)C=C1)=O)OC(C)C)C(NO)=O
Molecular Formula
C20H26N2O5S
Molecular Weight
406.50
References & Citations
[1]Jo YK, et al. ARP101, a selective MMP-2 inhibitor, induces autophagy-associated cell death in cancer cells. Biochem Biophys Res Commun. 2011;404 (4) :1039-1043.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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