S100B Polyclonal Antibody

• Background:

  The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly.

• Abbreviation:

  S100B

• UniProt:

  P50114

• Host:

  Rabbit

• Reactivity:

  Mouse; Rat

• Immunogen:

  Recombinant Mouse S100B protein expressed by E.coli

• Target:

  NEF; Protein S100 B; S 100 calcium binding protein beta chain; S100 protein beta chain; S-100 protein subunit beta; S100; S100 calcium-binding protein B; S100B; S100beta

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  IHC

• Field of Research:

  Cell Biology; Epigenetics and Nuclear Signaling; Stem Cells

• Purification:

  Antigen Affinity Purification

• Concentration:

  1 mg/mL

• Dilution:

  IHC 1:75-1:150

• Buffer:

  PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Isotype:

  IgG