Latanoprost acid

Latanoprost acid

• Product Name Alternative: UT-15
• CAS Number: 41639-83-2
• UNSPSC Description: Latanoprost acid, an analog of prostaglandin (PG) F2α, is an selective prostanoid receptor (FP) agonist that specifically activates the FP-PG receptor[1]. Latanoprost acid inhibits RANKL-induced osteoclastgenesis and function by inhibiting ERK, AKT, JNK, and p38 cascade, following by the c-fos/NFATc1 pathway. Latanoprost acid is a medication which works to lower pressure inside the eyes[2].
• Target Antigen: Prostaglandin Receptor
• Type: Reference compound
• Related Pathways: GPCR/G Protein
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/latanoprost-acid.html
• Purity: 99.62
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: O[C@@H]1[C@@H]([C@H]([C@@H](C1)O)CC[C@H](CCC2=CC=CC=C2)O)C/C=C\CCCC(O)=O
• Molecular Weight: 390.51
• References & Citations: [1]Weinreb RN, et al. Effects of prostaglandins on the aqueous humor outflow pathways. Surv Ophthalmol. 2002 Aug;47 Suppl 1:S53-64.|[2]Xu X, et al. The prevention of latanoprost on osteoclastgenesis in vitro and lipopolysaccharide-induced murine calvaria osteolysis in vivo. J Cell Biochem. 2018 Jun;119(6):4680-4691.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: Launched