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BT424

CAT: 0804-HY-155657-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-155657-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BT424 is a specific HCK inhibitor. BT424 can regulate macrophage activation and autophagy in vitro. BT424 ameliorates inflammation and kidney fibrosis in UUO model[1].
CAS Number
2755180-37-9
UNSPSC
12352005
Target
Src
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/bt424.html
Purity
98.89
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
ClC1=CC2=C(OC(C(C3=NOB(C4=CC=CC=C4)N3)=C2)C5=CC=CC=C5)C(Cl)=C1
Molecular Formula
C22H15BCl2N2O2
Molecular Weight
421.08
References & Citations
[1]Chen M, et al. HCK induces macrophage activation to promote renal inflammation and fibrosis via suppression of autophagy. Nat Commun. 2023 Jul 18;14 (1) :4297.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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