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(-) -Isodocarpin

CAT: 0804-HY-134046-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-134046-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(-) -Isodocarpin (Isodocarpin), a diterpenoid, is a potent melanogenesis inhibitor with an IC50 of 0.19 μM in B16 4A5 cells. (-) -Isodocarpin inhibits the expression of tyrosinase, tyrosine-related protein (TRP) -1, and TRP-2 mRNA[1].
CAS Number
10391-08-9
Product Name Alternative
Isodocarpin
UNSPSC
12352005
Target
Melanocortin Receptor
Type
Natural Products
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/minus-isodocarpin.html
Purity
99.78
Solubility
10 mM in DMSO
Smiles
O[C@H]1[C@@]2([H])[C@]3(CO1)[C@@]4([H])[C@@]5(C(O[C@@]3([H])CCC2(C)C)=O)C[C@@](C(C5=O)=C)([H])CC4
Molecular Formula
C20H26O5
Molecular Weight
346.42
References & Citations
[1]Yoshiaki Manse, et al. Melanogenesis Inhibitory Activity of Diterpenoid and Triterpenoid Constituents from the Aerial Part of Isodon trichocarpus. Natural Product Communications. August 1, 2017.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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