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NSC799462

CAT: 0804-HY-168005Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-168005Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NSC799462 is a triazole inhibitor of p97 ATPase. NSC799462 inhibits p97 ATPase activity (IC50 = 15 nM) by binding to a specific site on p97 and causing local changes in the p97 structure[1].
UNSPSC
12352005
Target
ATP Synthase; p97
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Membrane Transporter/Ion Channel
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nsc799462.html
Smiles
O=C(NC1CCN(C)CC1)OCC#CC2=C(F)C=C(OCC3=NN=C(S[C@H]4C=CCCC4)N3C5=CN=CC=C5)C=C2F
Molecular Formula
C30H32F2N6O3S
Molecular Weight
594.68
References & Citations
[1]Nandi P, et al. Mechanism of allosteric inhibition of human p97/VCP ATPase and its disease mutant by triazole inhibitors[J]. Communications Chemistry, 2024, 7 (1) : 177.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
T200146-01NSC799462

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