Endothelin B Receptor rabbit pAb
CAT:
855-ES20766-01
Size:
50 μL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Endothelin B Receptor rabbit pAb
- Description: The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Oct 2016],
- Synonyms: Endothelin B receptor (ET-B;ET-BR;Endothelin receptor non-selective type)
- Gene ID: 1910
- UniProt: P24530
- Cellular Locus: Cell membrane ; Multi-pass membrane protein. internalized after activation by endothelins..
- Host: Rabbit
- Species Reactivity: Human, Rat, Mouse
- Immunogen: Synthetic Peptide of Endothelin B Receptor AA range: 270-350
- Clonality: Polyclonal
- Validated Applications: IHC, IF
- Stability: 1 year
- Concentration: 1 mg/mL
- Dilution: IHC 1:100-200
- Molecular Weight: 50kD
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.