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CCT245232

CAT: 0804-HY-144867-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-144867-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CCT245232 is a potent inhibitor of heat shock factor 1 (HSF1) . HSF1 is the master regulator of the heat shock response, in which multiple genes are induced in response to temperature increase and other stresses. CCT245232 has the potential for the research of proliferative diseases, such as cancer (extracted from patent WO2015049535A1) [1].
CAS Number
1693731-14-4
UNSPSC
12352005
Target
HSP
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cct245232.html
Purity
99.37
Solubility
DMSO : 41.67 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C1=CC=C2N=C(C)C=CC2=C1)NC3=CC(NC(C4=CC=C5OCCOC5=C4)=O)=CC=C3C
Molecular Formula
C27H23N3O4
Molecular Weight
453.49
References & Citations
[1]Keith Jones, et al. Fused 1,4-dihydrodioxin derivatives as inhibitors of heat shock transcription factor 1. Patent WO2015049535A1.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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