Fluvoxamine

• Description :

  Fluvoxamine (DU-23000) is an antidepressant which functions pharmacologically as a selective serotonin reuptake inhibitor.

• Product Name Alternative :

  DU-23000

• UNSPSC :

  12352005

• Hazard Statement :

  H315, H319, H320

• Target :

  Serotonin Transporter

• Type :

  Reference compound

• Related Pathways :

  Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease; Cancer

• Assay Protocol :

  https://www.medchemexpress.com/fluvoxamine.html

• Purity :

  99.41

• Solubility :

  DMSO : 160 mg/mL (ultrasonic)

• Smiles :

  FC(C1=CC=C(/C(CCCCOC)=N/OCCN)C=C1)(F)F

• Molecular Formula :

  C15H21F3N2O2

• Molecular Weight :

  318.33

• Precautions :

  H315, H319, H320

• References & Citations :

  [1]Escalona, R., et al., Fluvoxamine treatment in veterans with combat-related post-traumatic stress disorder. Depress Anxiety, 2002. 15 (1) : p. 29-33.|[2]Ginsburg, B.C., J.W. Pinkston, and R.J. Lamb, The potency of fluvoxamine to reduce ethanol self-administration decreases with concurrent availability of food. Behav Pharmacol, 2012. 23 (2) : p. 134-42.|[3]Claassen, V., et al., Fluvoxamine, a specific 5-hydroxytryptamine uptake inhibitor. Br J Pharmacol, 1977. 60 (4) : p. 505-16.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  Launched

• Citation 01 :

  ACS Omega. 2025 Oct 17;10 (42) :50208-50217.|Int Immunopharmacol. 2024 Jan 25:127:111382.|Int Immunopharmacol. 2025 Jan 6:147:113969.|Mol Med. 2022 Aug 3;28 (1) :87.|Patent. US20250123269A1.|University of South Carolina. 2025.|Viruses. 2022 Jun 23;14 (7) :1369.|EMBO Mol Med. 2022 Jul 7;14 (7) :e15373.|Free Radic Biol Med. 2025 Jan:226:96-108.|Oxid Med Cell Longev. 2021 Jan 4;2021:8836818.|PLoS Negl Trop Dis. 2019 Aug 20;13 (8) :e0007681. |Research Square Preprint. 2023 Aug 10.|Sci Transl Med. 2019 Feb 6;11 (478) . pii: eaau5266.

• CAS Number :

  [54739-18-3]