Fluvoxamine

• UNSPSC Description:

  Fluvoxamine (DU-23000) is an antidepressant which functions pharmacologically as a selective serotonin reuptake inhibitor.

• Target Antigen:

  Serotonin Transporter

• Type:

  Reference compound

• Related Pathways:

  Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease; Cancer

• Assay Protocol:

  https://www.medchemexpress.com/fluvoxamine.html

• Purity:

  99.41

• Solubility:

  DMSO : 160 mg/mL (ultrasonic)

• Smiles:

  FC(C1=CC=C(/C(CCCCOC)=N/OCCN)C=C1)(F)F

• Molecular Weight:

  318.33

• References & Citations:

  [1]Escalona, R., et al., Fluvoxamine treatment in veterans with combat-related post-traumatic stress disorder. Depress Anxiety, 2002. 15(1): p. 29-33.|[2]Ginsburg, B.C., J.W. Pinkston, and R.J. Lamb, The potency of fluvoxamine to reduce ethanol self-administration decreases with concurrent availability of food. Behav Pharmacol, 2012. 23(2): p. 134-42.|[3]Claassen, V., et al., Fluvoxamine, a specific 5-hydroxytryptamine uptake inhibitor. Br J Pharmacol, 1977. 60(4): p. 505-16.Int Immunopharmacol. 2023 Dec 22:127:111382.|Mol Med. 2022 Aug 3;28(1):87.|Viruses. 2022, 14(7), 1369.|EMBO Mol Med. 2022 May 25;e15373.|Oxid Med Cell Longev. 2021 Jan 4;2021:8836818.|PLoS Negl Trop Dis. 2019 Aug 20;13(8):e0007681. |Research Square Preprint. 2023 Aug 10.|Sci Transl Med. 2019 Feb 6;11(478). pii: eaau5266.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  Launched

• CAS Number:

  54739-18-3