Vps34-IN-4
CAT:
804-HY-123058-04
Size:
25 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Vps34-IN-4
- CAS Number: 1383716-46-8
- UNSPSC Description: Vps34-IN-4 (compound 19) is a potent, selective, and orally active inhibitor of VPS34. Vps34-IN-4 inhibits the autophagy in vivo. Autophagy is a dynamic process that regulates lysosomal-dependent degradation of cellular components[1].
- Target Antigen: Autophagy; PI3K
- Type: Reference compound
- Related Pathways: Autophagy;PI3K/Akt/mTOR
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/vps34-in-4.html
- Purity: 99.19
- Solubility: DMSO : 78 mg/mL (ultrasonic)
- Smiles: CC(O)(C)CNC1=NC=C(C2=NC(NC3=CC=NC=C3)=NC=C2)C(CC4CC4)=N1
- Molecular Weight: 391.47
- References & Citations: [1]Honda A, et al. Potent, Selective, and Orally Bioavailable Inhibitors of VPS34 Provide Chemical Tools to Modulate Autophagy in Vivo. ACS Med Chem Lett. 2015;7(1):72-76.
- Shipping Conditions: Blue Ice
- Storage Conditions: -20°C, 3 years (Powder)
- Clinical Information: No Development Reported