Tenovin-3

• UNSPSC Description:

  Tenovin-3 is a p53 activator[1][2].

• Target Antigen:

  MDM-2/p53

• Type:

  Reference compound

• Related Pathways:

  Apoptosis

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/Tenovin-3.html

• Purity:

  98.0

• Solubility:

  DMSO : ≥ 31 mg/mL

• Smiles:

  O=C(NC(NC1=CC=C(N)C=C1)=S)C2=CC=C(C(C)(C)C)C=C2

• Molecular Weight:

  327.44

• References & Citations:

  [1]Lain S, et al. Discovery, in vivo activity, and mechanism of action of a small-molecule p53 activator. Cancer Cell. 2008 May;13(5):454-63.|[2]Jifei Miao, et al. Nuclear HMGB1 promotes the phagocytic ability of macrophages. Exp Cell Res. 2020 Aug 1;393(1):112037.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  1011301-27-1