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INCB9471

CAT: 0804-HY-14230Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-14230Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
INCB9471 is a potent, selective and orally active CCR5 antagonist. INCB9471 shows anti-HIV-1 activity[1][2].
CAS Number
869769-98-2
UNSPSC
12352005
Target
CCR; HIV
Type
Reference compound
Related Pathways
Anti-infection; GPCR/G Protein; Immunology/Inflammation
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/incb9471.html
Smiles
CCO[C@H]1[C@H](N2[C@H](CN(C3(CCN(CC3)C(C4=C(C)N=CN=C4C)=O)C)CC2)C)C5=CC=C(C(F)(F)F)C=C5C1
Molecular Formula
C30H40F3N5O2
Molecular Weight
559.67
References & Citations
[1]Shin N, et al. Identification and characterization of INCB9471, an allosteric noncompetitive small-molecule antagonist of C-C chemokine receptor 5 with potent inhibitory activity against monocyte migration and HIV-1 infection. J Pharmacol Exp Ther. 2011 Jul;338 (1) :228-39. |[2]Xue CB, et al. Discovery of INCB9471, a Potent, Selective, and Orally Bioavailable CCR5 Antagonist with Potent Anti-HIV-1 Activity. ACS Med Chem Lett. 2010 Aug 25;1 (9) :483-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
CCR5; HIV-1

Alternative Products

CatalogName
M16318-01INCB9471

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