Products for Research Use Only
RegisterLogin

Amino-PEG8-Boc

CAT: 0804-HY-W019799-01Size: 100 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-W019799-01Size:100 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Amino-PEG8-Boc is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Amino-PEG8-Boc is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
CAS Number
756526-06-4
UNSPSC
12352203
Hazard Statement
H302, H315, H319, H335
Target
ADC Linker; PROTAC Linkers
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/amino-peg8-boc.html
Purity
99.85
Solubility
10 mM in DMSO
Smiles
NCCOCCOCCOCCOCCOCCOCCOCCOCCC(OC(C)(C)C)=O
Molecular Formula
C23H47NO10
Molecular Weight
497.62
Precautions
H302, H315, H319, H335
References & Citations
[1]Hans-Georg Lerchen, et al. Antibody drug conjugates (adcs) and antibody prodrug conjugates (apdcs) with enzymatically cleavable groups. WO2016207089A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Alkyl/ether Linkers; Cleavable Linker; PEG Linkers

Chemical Information

1-Amino-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oic acid t-butyl ester
CAS Number756526-06-4
PubChem CID53433575
IUPAC Nametert-butyl 3-[2-[2-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
Molecular FormulaC23H47NO10
Molecular Weight497.6
XLogP-1.1
Topological Polar Surface Area126
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count11
Rotatable Bond Count28
Heavy Atom Count34
Formal Charge0
Complexity434
SMILES
CC(C)(C)OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCN
InChI
InChI=1S/C23H47NO10/c1-23(2,3)34-22(25)4-6-26-8-10-28-12-14-30-16-18-32-20-21-33-19-17-31-15-13-29-11-9-27-7-5-24/h4-21,24H2,1-3H3
InChIKey
UMJVFHNJPJVDSB-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 1-Amino-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oic acid t-butyl ester
CAS: 756526-06-4
CID: 53433575
Formula: C23H47NO10
MW: 497.6
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight497.6
XLogP3-1.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count11
Rotatable Bond Count28
Exact Mass497.31999670
Monoisotopic Mass497.31999670
Topological Polar Surface Area126 Ų
Heavy Atom Count34
Formal Charge0
Complexity434
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-140224-01Amino-PEG8-hydrazide-Boc
HY-138335Boc-PEG8-Boc
HY-130659-01Amino-PEG8-amine
HY-140385Ms-PEG8-Boc
HY-133212-01Mal-PEG8-Boc
HY-130375-01Propargyl-PEG8-Boc
HY-138340THP-PEG8-Boc
HY-130742-01Azido-PEG8-Boc
HY-141389Bromoacetamido-PEG8-Boc
HY-141368-01Bromo-PEG8-Boc

Alternative Products

CatalogName
BA2533-1000Amino-PEG8-Boc
GTR19215969-01Amino-PEG8-hydrazide-Boc
571855Amino-PEG8-t-Boc-hydrazide
T208055-01Boc-PEG8-Boc
T16004-01Mal-PEG8-Boc
T16649-01Propargyl-PEG8-Boc
MBS5771076m-PEG8-Boc
GTR19227024-01Bromoacetamido-PEG8-Boc
GTR19227102-01Bromo-PEG8-Boc
YPC79199Azido-PEG8-Boc

Popular Products