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Plathymenin

CAT: 0804-HY-N9115Size: InquireDry Ice: NoHazardous: No
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CAT#:0804-HY-N9115Size:Inquire
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
492-12-6
UNSPSC Description
Plathymenin is a flavonoid that can be isolated from Nepalese propolis. Plathymenin is a potent inhibitor of 5-LOX[1][2].
Target Antigen
Lipoxygenase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/plathymenin.html
Solubility
10 mM in DMSO
Smiles
O=C1C[C@@H](C2=CC=C(O)C(O)=C2)OC3=CC(O)=C(O)C=C13
Molecular Weight
288.25
References & Citations
[1]Funakoshi-Tago M, et al. Anti-inflammatory activity of flavonoids in Nepalese propolis is attributed to inhibition of the IL-33 signaling pathway. Int Immunopharmacol. 2015 Mar;25(1):189-98.|[2]Jiang S, et al. Combined Autodock and comparative molecular field analysis study on predicting 5-lipoxygenase inhibitory activity of flavonoids isolated from Spatholobus suberectus Dunn. Z Naturforsch C J Biosci. 2015;70(3-4):103-13.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported

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