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EtDO-P4

CAT: 0804-HY-50055-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-50055-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EtDO-P4 is a nanomolar inhibitor of glycosphingolipid (GSL) synthesis. EtDO-P4 suppresses activation of the EGFR-induced ERK pathway and various receptor tyrosine kinases (RTKs) . EtDO-P4 can be used for various types of cancer, including Burkitt’s lymphoma[1].
CAS Number
245329-78-6
UNSPSC
12352005
Target
ERK
Type
Reference compound
Related Pathways
MAPK/ERK Pathway; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/etdo-p4.html
Purity
98.75
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 80°C)
Smiles
O[C@H](C1=CC=C2C(OCCO2)=C1)[C@H](NC(CCCCCCCCCCCCCCC)=O)CN3CCCC3
Molecular Formula
C31H52N2O4
Molecular Weight
516.76
References & Citations
[1]Seung-Yeol Park, et al. Globoside promotes activation of ERK by interaction with the epidermal growth factor receptor. Biochim Biophys Acta. 2012 Jul;1820 (7) :1141-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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