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Allethrin

CAT: 0804-HY-B1559-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1559-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Allethrin, a pyrethroid insecticide is a major mosquito repellent agent. Allethrin induces oxidative stress, apoptosis and calcium release in rat testicular carcinoma cells (LC540) . Allethrin induces BCL-2, caspase-3 activation and release of intracellular calcium[1].
CAS Number
584-79-2
UNSPSC
12352211
Hazard Statement
H302+H332, H410
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/allethrin.html
Purity
98.04
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1C(C)(C)C1/C=C(C)\C)OC2C(C)=C(CC=C)C(C2)=O
Molecular Formula
C19H26O3
Molecular Weight
302.41
Precautions
H302+H332, H410
References & Citations
[1]Golla Madhubabu, et al. Allethrin induces oxidative stress, apoptosis and calcium release in rat testicular carcinoma cells (LC540) . Toxicol In Vitro. 2014 Dec;28 (8) :1386-95.|[2]Geetika Gupta, et al. Allethrin toxicity on human corneal epithelial cells involves mitochondrial pathway mediated apoptosis. Toxicol In Vitro. 2013 Dec;27 (8) :2242-8.|[3]Golla Madhubabu, et al. Allethrin induced toxicity in the male reproductive tract of rats contributes to disruption in the transcription of genes involved in germ cell production. Environ Toxicol. 2014 Nov;29 (11) :1330-45.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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