Methylmalonyl-CoA

• Description:

  Methylmalonyl coenzyme A (Methylmalonyl-CoA) is a catabolite of valine, isoleucine, methionine, threonine, odd-chain fatty acids, and cholesterol. Methylmalonyl coenzyme A tetralithium is converted to succinyl-CoA by enzymatic reaction of methylmalonyl-CoA mutase (MCM) with coenzyme vitamin B12[1].

• Product Name Alternative:

  Isosuccinyl coenzyme A; Methylmalonyl coenzyme A

• UNSPSC:

  12352204

• Hazard Statement:

  H315-H319-H335

• Target:

  Endogenous Metabolite

• Type:

  Enzyme

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/methylmalonyl-coa.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](COP(OP(OCC(C)(C)[C@@H](O)C(NCCC(NCCSC(C(C(O)=O)C)=O)=O)=O)(O)=O)(O)=O)O[C@H]1N2C=NC3=C(N)N=CN=C32

• Molecular Formula:

  C25H40N7O19P3S

• Molecular Weight:

  867.61

• Precautions:

  P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501

• References & Citations:

  [1]Gotoh K, et al. Assay for methylmalonyl coenzyme A mutase activity based on determination of succinyl coenzyme A by ultrahigh-performance liquid chromatography tandem mass spectrometry. Anal Bioanal Chem. 2015 Jul;407 (18) :5281-6.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Enzyme

• Clinical Information:

  No Development Reported

• CAS Number:

  [1264-45-5]