Methylmalonyl-CoA

• Product Name Alternative:

  Isosuccinyl coenzyme A; Methylmalonyl coenzyme A

• UNSPSC Description:

  Methylmalonyl coenzyme A (Methylmalonyl-CoA) is a catabolite of valine, isoleucine, methionine, threonine, odd-chain fatty acids, and cholesterol. Methylmalonyl coenzyme A tetralithium is converted to succinyl-CoA by enzymatic reaction of methylmalonyl-CoA mutase (MCM) with coenzyme vitamin B12[1].

• Target Antigen:

  Endogenous Metabolite

• Type:

  Enzyme

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/methylmalonyl-coa.html

• Solubility:

  10 mM in DMSO

• Smiles:

  NC1=NC=NC2=C1N=CN2[C@H]3[C@H](O)[C@H](OP(O)(O)=O)[C@@H](COP(O)(OP(O)(OCC(C)([C@H](C(NCCC(NCCSC(C(C(O)=O)C)=O)=O)=O)O)C)=O)=O)O3

• Molecular Weight:

  867.61

• References & Citations:

  [1]Gotoh K, et al. Assay for methylmalonyl coenzyme A mutase activity based on determination of succinyl coenzyme A by ultrahigh-performance liquid chromatography tandem mass spectrometry. Anal Bioanal Chem. 2015 Jul;407(18):5281-6.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1264-45-5