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DPhPC

CAT: 0804-HY-143202-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-143202-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DPhPC is a derivative of phosphatidylcholine (PC) used to synthesize bilayer vesicle phospholipids. DPhPC bilayer membranes do not leak ions in the absence of pores or ion channels, so they are often used to study the activity of ion channels and the regulation of membrane potential. Nanoliposomes (NTG) prepared based on DPhPC can improve the bioavailability of nitric oxide (NO) and have anti-inflammatory effects[1][2][3].
CAS Number
207131-40-6
UNSPSC
12352200
Hazard Statement
H315, H317, H319, H335, H360
Target
Biochemical Assay Reagents; Liposome
Type
Biochemical Assay Reagents
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/dphpc.html
Purity
99.77
Solubility
DMSO : 3.57 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CC(C)CCCC(C)CCCC(C)CCCC(C)CC(O[C@@H](COP(OCC[N+](C)(C)C)([O-])=O)COC(CC(C)CCCC(C)CCCC(C)CCCC(C)C)=O)=O
Molecular Formula
C48H96NO8P
Molecular Weight
846.25
Precautions
H315, H317, H319, H335, H360
References & Citations
[1]Schmidt D, et, al. A gating model for the archeal voltage-dependent K (+) channel KvAP in DPhPC and POPE:POPG decane lipid bilayers. J Mol Biol. 2009 Jul 31;390 (5) :902-12. |[2]Andersson M, et, al. Vesicle and bilayer formation of diphytanoylphosphatidylcholine (DPhPC) and diphytanoylphosphatidylethanolamine (DPhPE) mixtures and their bilayers' electrical stability. Colloids Surf B Biointerfaces. 2011 Feb 1;82 (2) :550-61.|[3]Ardekani S, et al. Nanoliposomal nitroglycerin exerts potent anti-inflammatory effects[J]. Scientific reports, 2015, 5 (1) : 16258.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported

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