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LDCA

CAT: 0804-HY-147361-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-147361-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LDCA is a dual-hit metabolic modulator and inhibits LDH-A enzyme activity to stimulate apoptosis in the malignant population. LDCA can be used for the research of oncogenic progression[1].
CAS Number
349106-80-5
UNSPSC
12352005
Hazard Statement
H302-H314
Target
Apoptosis; Lactate Dehydrogenase
Type
Reference compound
Related Pathways
Apoptosis; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ldca.html
Purity
99.18
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
FC1=C(Cl)C=C(NC(C(Cl)Cl)=O)C=C1
Molecular Formula
C8H5Cl3FNO
Molecular Weight
256.49
Precautions
P260-P264-P270-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P330-P363-P405-P501
References & Citations
[1]Saha, Suchandrima, et al. The dual-hit metabolic modulator LDCA synergistically potentiates doxorubicin to selectively combat cancer-associated hallmarks. RSC Advances, 7 (84), 53322–53333. doi:10.1039/c7ra08625c.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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